Hodgkin’s Disease following Prolonged Treatment with Phenytoin: A Case Report
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Current Issue: 2022, Volume 32, Issue 3
VOLUME: 11 ISSUE: 2
P: 87 - 90
December 2005

Hodgkin’s Disease following Prolonged Treatment with Phenytoin: A Case Report

Arch Epilepsy 2005;11(2):87-90
1. İzmir Atatürk Eğitim ve Araştırma Hastanesi 3. Nöroloji Kliniği, İzmir, Türkiye
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Received Date: 22.03.2005
Accepted Date: 11.08.2005
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ABSTRACT

Patients receiving phenytoin may develop benign lymphoid hyperplasia, pseudolymphoma, pseudo-pseudolymphoma, or rarely malignant lymphoma. A 76-year-old man who had been receiving phenytoin 300 mg/day for 25 years developed left axillary lymphadenopathy. A biopsy from the lesion revealed Hodgkin’s lymphoma. In this report, the patient’s clinical and histopathological symptoms and signs are presented and the association between phenytoin use and lymphoid pathologies is discussed.

Keywords:
Epilepsy, tonic-clonic/drug therapy, Hodgkin disease, lymphoma/chemically induced, phenytoin/ adverse effects