A Case of Frontotemporal Dementia with Epilepsia Partialis Continua Responding to Lacosamide Treatment
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    Case Report
    P: 40-44
    April 2019

    A Case of Frontotemporal Dementia with Epilepsia Partialis Continua Responding to Lacosamide Treatment

    Arch Epilepsy 2019;25(1):40-44
    1. Department of Neurology, Bilecik State Hospital, Bilecik, Turkey
    2. Department of Neurology, Dumlupınar University Evliya Çelebi Training and Research Hospital, Kütahya, Turkey
    No information available.
    No information available
    Received Date: 23.09.2017
    Accepted Date: 06.07.2018
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    ABSTRACT

    Seizures may occur in frontotemporal lobar degeneration syndromes as an element of a heterogeneous group of disorders, according to both clinical phenotype and neuropathology. Although electroencephalography results are abnormal in frontotemporal lobar degeneration syndromes, epileptic seizures are rarely reported. A better understanding of the pathogenesis of dementia may shed light on the mechanisms of epileptogenesis and may facilitate more rational approaches to seizure treatment. The treatment of seizures in dementia syndromes is still empiric. Epilepsia partialis continua (EPC) is included in the 2001 International League Against Epilepsy (ILAE) classification as a continuous type of seizure. According to the 2017 ILAE classification, the present patient’s seizure was defined as a focal onset, preserved consciousness, focal motor, clonic seizure. The onset of epilepsia partialis continua is usually a bad predictor of progressive disease. Furthermore, there is often a failure to respond to combined high dose antiepileptics, regardless of the underlying cause.

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