Senile Myoclonic Epilepsy in Down Syndrome with Dementia
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Case Report

Senile Myoclonic Epilepsy in Down Syndrome with Dementia

Arch Epilepsy 2011;17(2):61-64 DOI: 10.5505/epilepsi.2011.77487
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Abstract

We report a Down syndrome case with progressive deterioration of cognitive functions and myoclonic seizures. She had generalized tonicclonic seizure (GTCS) as well. The EEG showed slight diffuse slowing with frontal sharp-waves. Myoclonic jerks and GTCS persisted after lamotrigine; however, these seizures subsided with levetiracetam. Epilepsy in Down syndrome is associated with dementia, and all these points suggest that a common underlying physiopathology may exist.

Keywords: Dementia, Down syndrome, epilepsy