Original Article

Epilepsy in Elderly Patients

10.5505/epilepsi.2015.50470

  • Gülistan HALAÇ
  • Halide Rengi BİLGEN
  • Gülşen KOCAMAN
  • Elvin NİFTALİYEV
  • Çiğdem DENİZ
  • Talip ASİL

Received Date: 24.04.2015 Accepted Date: 31.05.2015 Arch Epilepsy 2015;21(2):59-64

Objectives:

The incidence of new-onset epilepsy is high among the elderly. This study presents the demographic characteristics, etiological factors, seizure types and response rates to treatment in a group of patients aged 65 years or over with delayed-onset epilepsy.

Methods:

The study comprised a retrospective evaluation of the records of 43 patients aged 65 or older with a diagnosis of delayed-onset epilepsy who were admitted to the epilepsy clinic in the Neurology Department of Bezmialem University Faculty of Medicine.

Results:

Patient mean age was 74.9 (66–92 years). Underlying disease was found to be cerebrovascular disease in 37.2%. Based on seizure type, 67.4% (n=29) patients had partial-onset and 32.6% (n=14) had generalized seizure. Treatment protocol in 93% (n=40) of the patients was monotherapy antiepileptic drugs, the most commonly used being levetiracetam (53.5%). Assessment of drug side effects showed no complaint in 86% (n=37) of the patients. During the three months prior to the study, 95.3% of the patients had been seizure free.

Conclusion:

The study found cerebrovascular disease to be the most common etiological factor in delayed-onset epilepsy. Partial-onset secondary generalized seizure was the most common seizure type. All patients responded well to monotherapy and have a good prognosis.

Keywords: Epilepsy, treatment, elderly patients